Lindley Darden Publications

Books

Craver, Carl F. and Lindley Darden (2013), In Search of Biological Mechanisms: Discoveries across the Life Sciences. Chicago, IL: University of Chicago Press.

Darden, Lindley (2006), Reasoning in Biological Discoveries. New York: Cambridge University Press. Available on Amazon

Darden, Lindley (1991), Theory Change in Science: Strategies from Mendelian Genetics. New York: Oxford University Press. (ISBN 0-19-506797-5 Oxford Press: 1-800-451-7556) 

Editor

Special Issue: Mechanisms in Biology, Studies in History and Philosophy of Biological and Biomedical Sciences. Introduction, "Mechanisms in Biology," Carl F. Craver and Lindley Darden, Guest Editors, "Introduction: Mechanisms Then and Now," June 2005.

Darden, Lindley (ed.) (1996), PSA 1996, Proceedings of the 1996 Biennial Meeting of the Philosophy of Science Association, Part I: Contributed Papers, Philosophy of Science, Supplement to Volume 63, September 1996.

Darden, Lindley (ed.) (1997), PSA 1996, Proceedings of the 1996 Biennial Meeting of the Philosophy of Science Association, Part II: Symposium Papers, Philosophy of Science, Supplement to Volume 64, December 1997.

Articles

Darden, Lindley (2013), "Mechanisms versus Causes in Biology and Medicine" in Hsiang-Ke Chao, Szu-Ting Chen, and Roberta L. Millstein (eds.), (2013) Mechanism and Causality in Biology and Economics. The Netherlands: Springer, pp. 19-34.

The historical case traces discovery of mechanism of cystic fibrosis.

Darden, Lindley (2009), "Discovering Mechanisms in Molecular Biology: Finding and Fixing Incompleteness and Incorrectness, " in J. Meheus and T. Nickles (eds.), Models of Discovery and Creativity. Dordrecht: Springer, pp. 43-55.

Darden, Lindley and Carl F. Craver (2009), "Reductionism in Biology," Invited and Refereed Keynote Article. Encyclopedia of Life Sciences. Chichester, UK: John Wiley & Sons, Ltd. Doi: 10.1002/9780470015902.a0003356

Darden, Lindley and James Tabery, "Molecular Biology," The Stanford Encyclopedia of Philosophy (2009 Edition), Edward N. Zalta (ed.),/

Darden, Lindley (2009), "Discovering Mechanisms in Molecular Biology: Finding and Fixing Incompleteness and Incorrectness, " in J. Meheus and T. Nickles (eds.), Models of Discovery and Creativity. Dordrecht: Springer, pp. 43-55.
Series: Origins: Studies in the Sources of Scientific Creativity , Vol.á3 DOI 10.1007/978-90-481-3421-2_3

Darden, Lindley (2008), "Thinking Again About Mechanisms," Philosophy of Science 75 (5): 958-969.

Darden, Lindley (2007), "Mechanisms and Models," in David L. Hull and Michael Ruse (eds.), Cambridge Companion to Philosophy of Biology. New York: Cambridge University Press, pp. 139-159.

Darden, Lindley (2006), "Flow of Information in Molecular Biological Mechanisms," Biological Theory 1 (3): 280-287.

Darden, Lindley (2006), "Anomaly Identification and Resolution for the Central Dogma of Molecular Biology, " in H-J. Rheinberger and S. de Chadarevian (eds.), History and Epistemology of Molecular Biology, Berlin: Max Planck Institute for History of Science, pp. 127-139.

Darden, Lindley (2005), "Relations Among Fields: Mendelian, Cytological and Molecular Mechanisms," Studies in History and Philosophy of Biological and Biomedical Sciences 36 (2005): 357-371.

Darden, Lindley and James Tabery (2005) "Molecular Biology," Stanford Encyclopedia of Philosophy

Darden, Lindley (2002), "Strategies for Discovering Mechanisms: Schema Instantiation, Modular Subassembly, Forward/ Backward Chaining," Philosophy of Science (Supplement PSA 2000 Part II) 69: S354-S365, preprint here)

Darden, Lindley (2002), "Discovering Mechanisms in Molecular Biology: Finding and Fixing Incompleteness and Incorrectness," in Jutta Schickore and Friedrich Steinle (eds.), Revisiting Discovery and Justification Berlin, Germany: Max Planck Institute for History of Science, pp. 143-154.

Darden, Lindley and Carl Craver (2002), "Strategies in the Interfield Discovery of the Mechanism of Protein Synthesis," Studies in History and Philosophy of Biological and Biomedical Sciences 33: 1-28.

Darden, Lindley (2001), "Discovering Mechanisms: A Computational Philosophy of Science Perspective," in Klaus P. Jantke and Ayumi Shinohara (eds.), Discovery Science (Proceedings of the 4th International Conference, DS2001). New York: Springer-Verlag, pp. 3-15. 

Craver, Carl and Lindley Darden (2001), "Discovering Mechanisms in Neurobiology: The Case of Spatial Memory," in Peter Machamer, R. Grush, and P. McLaughlin (eds.), Theory and Method in Neuroscience. Pittsburgh, PA: University of Pittsburgh Press, pp. 112-137. 

Machamer, Peter, Lindley Darden, and Carl Carver (2000), " Thinking About Mechanisms," Philosophy of Science 67: 1-25.

Darden, Lindley (1998), "Anomaly-Driven Theory Redesign: Computational Philosophy of Science Experiments," in Terrell W. Bynum and James Moor (eds.), Digital Phoenix: How Computers are Changing Philosophy, Oxford: Blackwell, pp. 62-78. 

Darden, Lindley (1997), "Recent Work in Computational Scientific Discovery," in Michael G. Shafto and Pat Langley (eds.), Proceedings of the Nineteenth Annual Conference of the Cognitive Science Society, Mahwah, New Jersey: Lawrence Erlbaum, pp. 161-166. 

Darden, Lindley (1995), "Exemplars, Abstractions, and Anomalies: Representations and Theory Change in Mendelian and Molecular Genetics," in James G. Lennox and Gereon Wolters (eds.), Concepts, Theories, and Rationality in the Biological Sciences. Pittsburgh, PA: University of Pittsburgh Press, pp. 137-158. 

Darden, Lindley and Michael Cook (1994), "Reasoning Strategies in Molecular Biology: Abstractions, Scans and Anomalies," in D. Hull, M. Forbes, and R. M. Burian (eds.), PSA 1994, v. 2. East Lansing, Michigan: Philosophy of Science Association, pp. 179-191.

Darden, Lindley (1993), "Interfield Theories and Strategies for Theory Change," in Hans V. Rappard, Pieter J. Van Strien, Leendert P. Mos, and William J. Baker (eds.), Annals of Theoretical Psychology, v. 9. New York: Plenum Press, pp. 141-144. 

Darden, Lindley (1992), "Strategies for Anomaly Resolution," in R. Giere (ed.), Cognitive Models of Science, Minnesota Studies in the Philosophy of Science, Vol. 15. Minneapolis: University of Minnesota Press, pp. 251-273.

Darden, Lindley; Moberg, Dale; Thadani, Sunil; and Josephson, John (July 1992), "A Computational Approach to Scientific Theory Revision: The TRANSGENE Experiments," Technical Report 92-LD-TRANSGENE, Laboratory for Artificial Intelligence Research, The Ohio State University.

Darden, Lindley; Dale Moberg; Satish Nagarajan; and John Josephson (1991), "Anomaly Driven Redesign of a Scientific Theory: The TRANSGENE.2 Experiments," Technical Report 91-LD-TRANSGENE. Laboratory for Artificial Intelligence Research, The Ohio State University, Columbus, Ohio.

Darden, Lindley and Moberg, Dale (1990), "Representing and Reasoning about Biological Theories Using the Functional Representation System," Working Notes, AAAI Spring Symposium on Artificial Intelligence and Molecular Biology, Stanford, California, March 1990, pp. 95-97.

Darden, Lindley (1990), "Diagnosing and Fixing Faults in Theories," in J. Shrager and P. Langley (eds.), Computational Models of Scientific Discovery and Theory Formation. San Mateo, California: Morgan Kaufmann, pp. 319-346. 

Darden, Lindley and Cain, Joseph A. (1989), "Selection Type Theories," Philosophy of Science 56:106-129.

Cain, Joseph A. and Darden, Lindley (1988), "Hull and Selection," Biology and Philosophy 3 :l65-l71.

Darden, Lindley and Roy Rada (1988b), "Hypothesis Formation Via Interrelations," in Armand Prieditis (ed.), Analogica. Los Altos, California: Morgan Kaufmann, pp. 109-127.

Darden, Lindley and Roy Rada (1988a), "Hypothesis Formation Using Part-Whole Interrelations," in David Helman (ed.), Analogical Reasoning. Dordrecht: Reidel, pp. 341-375. 

Darden, Lindley (1987), "Viewing the History of Science as Compiled Hindsight," AI Magazine 8(2):33-41.

Darden, Lindley (1986), "Relations among Fields in the Evolutionary Synthesis," in W. Bechtel (ed.), Integrating Scientific Disciplines. Dordrecht: Nijhoff, pp. 113-123.

Darden, Lindley (1986), "Reasoning in Theory Construction: Analogies, Interfield Connections, and Levels of Organization," in Paul Weingartner and Georg Dorn (eds.), Foundations of Biology. Vienna, Austria: HÓlder-Pichler-Tempsky, pp. 99-107.

Darden, Lindley (1985), "Hugo de Vries's Lecture Plates and the Discovery of Segregation," Annals of Science 42:233-242. 

Darden, Lindley (1982), "Aspects of Theory Construction in Biology," in Proceedings of the Sixth International Congress for Logic, Methodology and Philosophy of Science. Hanover: North Holland Publishing Co., pp. 463-477. 

Darden, Lindley (1982), "Artificial Intelligence and Philosophy of Science: Reasoning by Analogy in Theory Construction," in T. Nickles and P. Asquith (eds.), PSA 1982, V. 2. East Lansing, Michigan: Philosophy of Science Association, pp. 147-165. 

Darden, Lindley (1980), "Theory Construction in Genetics," in T. Nickles (ed.), Scientific Discovery: Case Studies. Dordrecht: Reidel, pp. 151-170.

Darden, Lindley (1978), "Discoveries and the Emergence of New Fields in Science," in P.D. Asquith and I. Hacking (eds.), PSA 1978, V. 1. East Lansing, Michigan: Philosophy of Science Association, pp. 149-160.

Darden, Lindley and Nancy Maull (1977),"Interfield Theories," Philosophy of Science 44:43-64. 

Excerpts reprinted in Interdisciplinary Analysis and Research, ed. D. Chubin, A. Porter, F. Rossini, and T. Connolly, Lomond Publication, Mt. Airy, Maryland, 1986, pp. 307-321. (A response to W. Woodward and D. Devonis, "Toward a New Understanding of Scientific Change: Applying Interfield Theory to the History of Psychology" same volume.)

Excerpts reprinted in Schick, Theodore, Jr. (ed.), Readings in the Philosophy of Science: From Positivism to Postmodernism. Mountain View, CA: Mayfield Publishing Company, 2000, pp. 138-147.

Darden, Lindley (1977), "William Bateson and the Promise of Mendelism," Journal of the History of Biology 10:87-106. 

Darden, Lindley (1976), "Reasoning in Scientific Change: Charles Darwin, Hugo de Vries, and the Discovery of Segregation," Studies in History and Philosophy of Science 7:127-169. 

Darden, Lindley (1974), "Reasoning in Scientific Change: The Field of Genetics at Its Beginnings," Ph.D. Dissertation, Committee on the Conceptual Foundations of Science, University of Chicago, Chicago, Illinois.

Reviews

Review of James T. Costa's The Annotated Origin: A Facsimile of the First Edition of On the Origin of Species, by Charles Darwin, with Introduction and Notes, Annals of Science (2011 online first): 1-3. DOI: 10.1080/00033790.2010.518769

Review of William Bechtel's Discovering Cell Mechanisms, in Journal of the History of Biology (2007): 185-187.

Review of Marcel Weber's Philosophy of Experimental Biology, ISIS 97 (March 2006); 198-199.

Review of Michael Ruse's Darwin and Design: Does Evolution Have a Purpose? in ISIS, 95 (2004): 338-339.

Review of Nathaniel C. Comfort's The Tangled Field: Barbara McClintock's Search for the Patterns of Genetic Control in Bulletin of the History of Medicine 77 (2003) 987-989.

Review of Paul Thagard, How Scientists Explain Disease, in Philosophy of Science  67 (2000): 352-354.

Darden, Lindley (1996), "Generalizations in Biology," Essay Review of K. Schaffner's Discovery and Explanation in Biology and Medicine in Studies in History and Philosophy of Science 27: 409-419.

Darden, Lindley (1997) "Discovering Complexity" Essay Review of William Bechtel and Robert Richardson's Discovering Complexity in Biology and Philosophy 12:101-107.

Strom, John and Lindley Darden (1996), Essay review of "Is Artificial Intelligence a Degenerating Program: A Review of Hubert Dreyfus' What Computers Still Can't Do," in Artificial Intelligence 80:151-170.

Darden, Lindley (1995), Review of Scott Kleiner's Logic of Discover in Philosophical Psychology 8 (1995) 426-429.

Amann, Stefan and Lindley Darden (1990), Review of John Losee's Philosophy of Science and Historical Enquiry in Quarterly Review of Biology 65:57-58.

Darden, Lindley (1990), Review of Paul Thagard's Computational Philosophy of Science, in Isis 81:153-154.

Darden, Lindley (1988), Review of Edward D. Garber (ed.), Genetic Perspectives in Biology and Medicine, in Journal of the History of Medicine and Allied Sciences, 43:90-92.

Darden, Lindley (1986), Review of E. Sober's, The Nature of Selection: Evolutionary Theory in Philosophical Focus, in Teaching Philosophy 9:365-366.

Darden, Lindley (1983), Review of D. R. Griffin's The Question of Animal Awareness, 2nd. ed., in British Journal for the Philosophy of Science 34:399-403. 

Darden, Lindley (1983), Review of E.A. Carlson's Genes, Radiation and Society: The Life and Work of H.J. Muller in Journal of the History of Medicine and Allied Sciences 38:369-371. 

Darden, Lindley (1980), Review of Garland Allen's Thomas Hunt Morgan in Philosophy of Science 47:662-666.

Darden, Lindley (1980), Review of A. Caplan's The Sociobiology Debate and Michael Ruse's Sociobiology: Sense or Nonsense? in Isis 71:653-654.

Darden, Lindley (1979), Review of John Farley's The Spontaneous Generation Controversy from Descartes to Oparin in Origins of Life 9:352.


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